What is Periodontal Disease and
how is it connected to heart disease and premature birth?

 

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Over the past several months periodontal disease has become front page news as the medical and dental communities have begun to discuss whether periodontal disease is related to premature births and heart disease. The purpose of this up-date letter is to explain periodontal disease itself, and what is known about periodontal disease and its connection to low-birth weight and heart attacks.

In excess of three-quarters of adults 35 and over have some degree of periodontal disease. Most individuals are familiar with the symptoms of periodontal disease such as bad breath, frequent gum infections, swollen gums, gums which bleed or loose teeth. The disease itself is best understood as a chronic bacterial infection. As bacteria build up under the gum line, a low grade infection begins to emerge in the gum tissue. The gum tissue itself reacts to the infection by becoming inflamed and swollen. This is known as gingivitis. If the level of bacteria is not reduced, the infection spreads to the bone that supports the tooth and the attachment between the bone, gum and tooth becomes destroyed. At this point, periodontal disease has begun. The missing attachment between the bone and gum becomes a periodontal pocket that contains billions of bacteria. As the bacteria under the gum line continues to build to a higher and higher level, the bacteria itself becomes more dangerous as it inflicts greater harm by causing more extensive bone loss and deeper pockets. In the end, tooth loss will result.

Now we are learning that in addition to causing tooth loss, periodontal disease may trigger premature births and cause heart attacks. In discussing periodontal disease and its connection to other diseases, the first point to be emphasized is that there is no concrete proof linking gum disease with heart disease and low-weight births. However, recent studies on periodontal disease strongly suggest that individuals with periodontal disease have a higher risk of heart disease, and that periodontal disease may be responsible for low weight births.

Looking at heart disease, periodontal disease is thought to contribute to heart attacks by releasing bacteria located in infected gum tissue into the bloodstream which then travels throughout the body. Over time the infectious bacteria inflicts damage by causing arteries to become obstructed. Periodontal disease is being looked at as a cause of artery congestion as germs associated with periodontal disease exhibit clogging properties. For example, the bacteria Porphyromanas Gingivalis cause blood to clot. In addition, gum germs have been found in artery-plugging plaque.

Studies examining periodontal disease and its relationship to heart disease indicate that individuals with a periodontal condition are at a greater risk of heart disease. One such study, done in Wisconsin, followed the health of 9,760 Americans from the early 1970s to date. Men who had gum disease when the study began had a 75% greater risk of heart trouble than those who had no periodontal problems. Another study followed 1,231 men who were outwardly healthy when given dental exams in the 1960s. In the years that followed, men who started out with gum problems had twice the rate of death from heart disease.

Gum disease may also be a major contributing factor in low-weight births. The Journal of Periodontology has reported that periodontal infection may be responsible for as many as 18% of all births under 5.5 pounds in the United States each year. Bacteria appear to retard fetal growth by releasing toxins that reach the placenta and interfere with fetal development. In addition, periodontal bacteria appear to cause the uterus to contract setting off premature labor.

As I discussed, there is no definitive proof that periodontal problems cause heart disease and premature births. However, the evidence suggests that something as simple as treating gum disease may lower other health risks. Which brings me to the good news about periodontal disease - in most cases it is entirely preventable and controllable. Brushing, flossing and manual plaque removal are effective in preventing and managing gum disease. We know that such therapy helps keep the bacterial load below the level at which tissue loss is triggered. Such therapy may also keep bacterial build-up from reaching the level at which periodontal germs are released into the blood stream.

As many of you are aware, my philosophy of patient treatment is that of preventive care. I have previously emphasized preventive treatment in terms of catching tooth decay. Preventive treatment is also of the utmost importance in catching periodontal disease. In this respect, I cannot emphasize enough the importance of regular hygiene exams to detect gum disease as it begins to develop. In addition, regular cleanings combined with proper home care are effective in keeping germ levels below the point at which gums become infected and periodontal disease begins to develop.

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