Brush Biopsy

 

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While a biopsy is the definitive way to determine if any lesion is pre malignant, malignant or benign, a recent advancement has been made in the detection of oral cancers through the use of a procedure called the brush biopsy. The brush biopsy allows the testing of any lesion, which is suspicious but lacks any clinical evidence of malignancy without subjecting the patient to an invasive biopsy.

Testing with the brush biopsy involves placing a brush against the suspicious lesion and rotating the brush. The material collected on the brush is transferred to a glass slide and sent for laboratory testing. At the laboratory, a computer analyzes the slide and the computer output is then used by a pathologist in conjunction with a standard microscopic evaluation of each specimen. A positive result must still be followed-up with a scalpel biopsy.

The brush biopsy has been found to have a zero false-negative rate, and, most importantly, has been found to increase early detection of oral cancers.

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